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Description

J.et al (2013)

Retatrutide represents a promising pipeline compound that could expand the therapeutic toolkit, especially for patients with concurrent MASLD/MASH where glucagon-mediated hepatic fat oxidation may provide additional benefit

Stem Cells 35 (7), 18151834

They address different problems and are sometimes used together in the same patient

Ouabain downregulated SLC7A11, reduced cysteine uptake and subsequently inhibited glutathione synthesis, probably through inhibiting Akt/mTOR/beclin axis that regulate protein activity of SLC7A11